And they come with no warning,
nature loves her little surprises.
Continual crisis!

Monday, December 12, 2011

Small Aggravations

Okay, so, for exotoxins of microbes (the toxins the microbes create and shed, as compared to the toxins formed within the microbe that are released as the microbe is lysed - destroyed - which are endotoxins), there can be a two part system referred to as A-B. They're two different toxins (proteins), but here the B helps the A into the cell. The B has the receptors to attach to the cell wall, which then causes phagocytosis - the cell "eats" it. The A part attaches to the B part, so when the B gets eaten, so does the A. Now, in most cases, the B doesn't do much of anything else. It's the A protein that causes the problems (acts as the toxin).

With me so far?

Clostridium difficile (C. diff), has two enterotoxins (toxins that work in your GI tract) called A and B.

Sigh. Really? REALLY? We couldn't call them C and D (you know, for C. diff)? One of the reasons this shit is so hard. Don't even get me started on "di-" versus "bis-" prefixes.

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